About Propecia
This is a
simplified report on Propecia and is not intended to replace discussions with a
healthcare provider. Do not use this information as a substitute for your
doctor's advice. Always consult your doctor before taking any drug and follow
your doctor's directions.
What is
Propecia?
Propecia
is the brand name of the drug finasteride, also sold as proscar. It's the first
pill approved by the FDA to treat male pattern baldness or hair loss on the top
of the head and mid-scalp areas. Finasteride is pronunciation: fin AS ter ide.
Propecia was originally developed to treat an enlarged prostate condition called
benign prostatic hyperplasia (BPH). The FDA approved it in December 22, 1997.
It's manufactured by Merck and Company, Inc.
How does
Propecia work?
Male
pattern baldness is medically called androgenetic alopecia. It accounts for 95%
of all hair loss. In women, it appears as a diffuse thinning over most of the
scalp. In men, it starts with a receding hairline that gradually develops over
the top of the head. This hair loss is called androgenetic alopecia because the
male hormones (androgens) and hereditary factors (genetic) that determine the
loss of hair.
Specifically, the enzyme 5 alpha reductase converts the male hormone
testosterone into a male hormone called Dihydrotestosterone (DHT). The DHT is
believed to cause hair loss in those who are genetically disposed. DHT shrinks
the hair follicle until it no longer grows visible hair.
Propecia works by blocking the enzyme 5 alpha reductase that lowers the levels
of DHT in the body. This normalizes hair growth and reverses hair loss. The
advantage of Propecia is that it selectively targets the appropriate hormone
without causing undesirable changes in other hormones.
What
side effects do users of Propecia report?
98% of
men taking Propecia had no side effects. Clinical tests show PROPECIA is very
well tolerated. A small number of men (1.8%) experience some sexual side
effects. 1.3% reported erectile dysfunction.
Tell your doctor if you experience
Decreased libido (1.8%)
Decreased volume of ejaculate (0.8%)
Impotence
Breast tenderness or enlargement.
May cause birth defects in male baby's sex organs if taken by women.
In all cases of men who reported side effects, stopping the medication resolves
the problem. In those who stopped taking it, the benefits gradually declined and
hair loss resumed.
Storing
Propecia
Store
Propecia in a tightly closed container at room temperature ( 59 - 86 degrees F
or 15 - 30 degrees C) away from heat and moisture.
Conditions you should tell your Doctor about before taking Propecia:
If you're
going to get a blood test for PSA (Prostate Specific Antigen), the Propecia will
alter the results.
Liver disease - you may need a lower dose or special monitoring during therapy.
Tell
Your Doctor if you are taking any of the following medicines:
Though no
known conflicts have been reported, you should still tell your doctor in case
something new has been discovered.
General
Notes on Propecia
If you
miss a day, do NOT take an extra tablet. Taking more than one a day is NOT
recommended.
You may use it for 3 months or more before you notice an increase in hair growth
and/or prevention of hair loss. If you haven't seen results within 12 months,
you probably won't.
You have to use it continuously for maximum benefit. If you stop taking it, you
will likely lose the hair you have gained within 12 months.
Take each dose with a full glass of water (8 ounces).
Propecia has been studied in men with mild to moderate hair loss, aged 18 to 41.
Not to be used or given to anyone under the age of 18.
Not to be used by women - causes birth defects.
Women should not handle crushed or broken Propecia tablets. It can be absorbed
through the skin. Whole tablets are coated to prevent this.
Can be taken with or without food.
According to Merck Pharmaceuticals, Propecia stops the progression of hair loss
in the majority of patients (83%), and results in hair regrowth in over 65%.
Tests were performed for semen levels in 35 men taking PROPECIAŽ daily for 6
months. PROPECIAŽ levels were undetectable in 60% of the samples. The highest
level measured was 1.52 ng/mL and the mean was 0.26 ng/mL. Using the highest
semen level measured, a woman's exposure through vaginal absorption would be 750
times lower than the exposure from the no-effect dose in Rhesus monkeys tests.
PROPECIAŽ helps grow natural hair not just "peach fuzz" and it's as convenient
as taking a vitamin: one pill a day.
Some studies shown Propecia to be about 80% effective in preventing future hair
loss and about 40% - 50% effective in restoring hair growth.